Vilar oscillator

Scatter plot of Da' vs. R for Vilar oscillator from t=0 to t=100 (hrs)

The circadian rhythm is a well-known cellular phenomenon, commonly known as the “biological clock”, and modeled by the Vilar oscillator. The version of the Vilar oscillator used here it is a system of 9 species and 16 reaction channels.

It is chosen, not so much for its stiffness, which is on a par with HSR (below), but because its stochastic resonance means that it is particularly ill-suited to deterministic simulation, and particularly well-suited to SSA.

SBML Model.